Thanks to the collaborative work of the SCF doctors and genetic counselors, the CCXDP researchers and the participation of our XDP patients, recent genetic mapping studies have pinpointed the likely cause of XDP to a disease-specific retrotransposon insertion in the human TAF1 gene. Results have shown how this DNA insertion has a repeitive sequence, which can decrease TAF1 gene expression. The goal now of researchers is how to normalize the TAF1, which may possibly lead to the cure. This discovery is an incredible feat, raising hopes for a lasting solution.
The Sunshine Care Foundation Inc., 2F
The Health Centrum, Teodorica Avenue, Banica, Roxas City, Philippines
The Sunshine Care Foundation Inc.,
Metro Iloilo and Medical Center, Metropolis Avenue, Iloilo City, Philippines